Description

2-(5,6-Dibromo-1,3-Dioxooctahydro-2H-4,7-Methano-Isoindol-2-Yl)-3-Phenylpropanoic Acid is a specialized brominated heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique bridged isoindole structure, functionalized with bromine atoms and a carboxylic acid group, makes it a valuable building block for constructing complex molecular architectures. This high-purity intermediate is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Advanced Organic Synthesis: Serves as a versatile building block for constructing complex, polycyclic frameworks in medicinal chemistry and material science.
• Agrochemical Research: Used in the synthesis of experimental herbicides and pesticides, leveraging its halogenated structure.
• Chemical Biology Probes: Employed in the development of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Polymer Modification: Potential monomer or additive for creating specialty polymers with specific thermal or optical properties.
• Academic & Industrial R&D: Essential reagent for methodological studies in synthetic organic chemistry and catalysis.

Basic Information

Product Name	2-(5,6-Dibromo-1,3-Dioxooctahydro-2H-4,7-Methano-Isoindol-2-Yl)-3-Phenylpropanoic Acid
CAS No.	386702-34-7
Molecular Formula	C18H17Br2NO4
Molecular Weight	479.14 g/mol
Synonyms	2-(5,6-Dibromo-1,3-dioxooctahydro-2H-4,7-methano-isoindol-2-yl)-3-phenylpropanoic acid; 3-Phenyl-2-(5,6-dibromo-1,3-dioxo-4,7-methano-2,3,3a,4,7,7a-hexahydro-1H-isoindol-2-yl)propanoic acid; 2-(5,6-Dibromo-1,3-dioxo-4,7-methano-isoindolin-2-yl)-3-phenylpropionic acid; DBMI-PPA; NSC 796379; Dibromomethanoisoindolepropanoic Acid
EINECS	Contact for details

Quality Control

Our 2-(5,6-Dibromo-1,3-Dioxooctahydro-2H-4,7-Methano-Isoindol-2-Yl)-3-Phenylpropanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.