Description

6-Azabicyclo[3.1.0]Hexane-2,3,4-Triol, 6-Methyl-, (1Alpha,2Alpha,3Alpha,4Alpha,5Alpha)- (9Ci) is a complex, stereochemically defined bicyclic amino polyol compound. This molecule serves as a high-value, multifunctional chiral building block critical for constructing sophisticated pharmacophores in modern drug discovery. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel therapeutic agents, particularly in areas requiring rigid, three-dimensional molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel antiviral, antibacterial, or neurological drug candidates.
• Advanced Organic Synthesis: Used as a constrained scaffold to introduce multiple hydroxyl and amine functionalities in complex natural product analogs and chemical probes.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new bioactive chemical space due to its unique bicyclic[3.1.0] framework.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands used in asymmetric catalysis.
• Bioconjugation Chemistry: The polyol structure can be functionalized for linking biomolecules or creating specialized linkers.
• Academic & Industrial R&D: A valuable compound for methodological development in synthetic organic chemistry and chemical biology.

Basic Information

Product Name	6-Azabicyclo[3.1.0]Hexane-2,3,4-Triol, 6-Methyl-, (1Alpha,2Alpha,3Alpha,4Alpha,5Alpha)- (9Ci)
CAS No.	385443-39-0
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	(1α,2α,3α,4α,5α)-6-Methyl-6-azabicyclo[3.1.0]hexane-2,3,4-triol; 6-Methyl-6-azabicyclo[3.1.0]hexane-2,3,4-triol (stereoisomer); 6-Azabicyclo[3.1.0]hexane-2,3,4-triol, 6-methyl-, (1α,2α,3α,4α,5α)-; Bicyclic amino polyol derivative; CAS 385443-39-0; Chiral azabicyclohexanetriol.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) detailing all relevant specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container should be stored in a cool, dry place, ideally under an inert atmosphere such as nitrogen or argon for long-term storage. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.