Description

Methanone, (6-Chloro-3-Pyridinyl)(2-Methyl-1-Piperidinyl)- is a specialized organic compound featuring a ketone (methanone) core linked to a chloropyridine and a methyl-substituted piperidine moiety. This unique molecular architecture makes it a valuable advanced intermediate for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists for constructing novel active ingredients, where its specific substitution pattern is critical for achieving desired biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) targets, receptor modulators, and kinase inhibitors.
• Agrochemical Research: Used in developing novel insecticides, herbicides, or fungicides, leveraging the bioactivity of the chloronicotinyl and piperidine components.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of libraries of compounds for high-throughput screening in discovery chemistry.
• Ligand and Catalyst Development: The nitrogen-containing heterocycles make it a candidate for developing chelating ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	Methanone, (6-Chloro-3-Pyridinyl)(2-Methyl-1-Piperidinyl)-
CAS No.	385408-28-6
Molecular Formula	C12H15ClN2O
Molecular Weight	238.71 g/mol
Synonyms	(6-Chloro-3-pyridinyl)(2-methyl-1-piperidinyl)methanone; 2-Methyl-1-(6-chloropyridin-3-yl)(piperidin-1-yl)methanone; 1-(6-Chloro-3-pyridinyl)-2-methyl-1-piperidinylmethanone; (6-Chloro-3-pyridyl)(2-methyl-1-piperidyl)methanone; 385408-28-6; (6-Chloro-pyridin-3-yl)-(2-methyl-piperidin-1-yl)-methanone
EINECS	Contact for details

Quality Control

Our production of Methanone, (6-Chloro-3-Pyridinyl)(2-Methyl-1-Piperidinyl)- CAS 385408-28-6 adheres to strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.