Description

Ethyl 6-Bromo-2-(tert-Butyl)-5-Hydroxybenzofuran-3-Carboxylate is a high-purity, synthetic benzofuran derivative, a key building block in advanced organic synthesis. This compound is valued for its specific bromine and hydroxyl functional groups, which enable precise chemical modifications in complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical development companies engaged in creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its benzofuran core structure.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and cross-coupling reactions.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Ethyl 6-Bromo-2-(tert-Butyl)-5-Hydroxybenzofuran-3-Carboxylate
CAS No.	384368-90-5
Molecular Formula	C₁₅H₁₇BrO₄
Molecular Weight	341.20 g/mol
Synonyms	6-Bromo-2-tert-butyl-5-hydroxy-1-benzofuran-3-carboxylic acid ethyl ester; Ethyl 6-bromo-2-(1,1-dimethylethyl)-5-hydroxy-1-benzofuran-3-carboxylate; 2-tert-Butyl-6-bromo-5-hydroxybenzofuran-3-carboxylic acid ethyl ester; 384368-90-5; 6-Bromo-2-(tert-butyl)-5-hydroxybenzofuran-3-carboxylic acid ethyl ester; Benzofuran-3-carboxylic acid, 6-bromo-2-(1,1-dimethylethyl)-5-hydroxy-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-2-(tert-Butyl)-5-Hydroxybenzofuran-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.