Description

4-(4-Fluorophenyl)-1,3-thiazole is a high-purity fluorinated heterocyclic compound serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a fluorinated aromatic ring with a thiazole heterocycle, making it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas like kinase inhibitors and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, including OLEDs and semiconductors, due to its electron-deficient thiazole core.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for transition metal catalysis and organocatalysts.
• Fluorine Chemistry Studies: A valuable substrate for exploring new fluorination reactions and studying structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	4-(4-Fluorophenyl)-1,3-thiazole
CAS No.	383145-29-7
Molecular Formula	C9H6FNS
Molecular Weight	179.21 g/mol
Synonyms	4-(4-Fluorophenyl)thiazole; 4-(p-Fluorophenyl)thiazole; 1,3-Thiazole, 4-(4-fluorophenyl)-; 4-(4-Fluorophenyl)-1,3-thiazole; 4-(4-Fluorophenyl)thiazole; p-Fluorophenylthiazole; 4-(4-Fluorophenyl)-δ²-thiazoline
EINECS	Contact for details

Quality Control

Our 4-(4-Fluorophenyl)-1,3-thiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades, from research (≥95%) to pharmaceutical intermediate (≥98%) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.