Description

1-(2-Bromo-4-Fluorophenyl)-1H-Pyrrole is a high-purity, heterocyclic aromatic compound featuring a pyrrole ring substituted with a bromo-fluorophenyl group, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique halogenated structure makes it an indispensable building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for its versatility in cross-coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the halogen atoms for further derivatization.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of the bromine atom.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for transition metal catalysis.
• Chemical Biology Probes: Incorporated into molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	1-(2-Bromo-4-Fluorophenyl)-1H-Pyrrole
CAS No.	383137-41-5
Molecular Formula	C10H7BrFN
Molecular Weight	240.07 g/mol
Synonyms	1-(2-Bromo-4-fluorophenyl)-1H-pyrrole; 2-Bromo-4-fluoro-1-(1H-pyrrol-1-yl)benzene; 1H-Pyrrole, 1-(2-bromo-4-fluorophenyl)-; 383137-41-5; 2-Bromo-4-fluorophenyl pyrrole; 1-(2-Bromo-4-fluorophenyl)pyrrole; N-(2-Bromo-4-fluorophenyl)pyrrole
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-4-Fluorophenyl)-1H-Pyrrole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material for regulatory filings. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.