Description

7-(3-Chloro-Propoxy)-4-(2,4-Dichloro-5-Methoxy-Phenylamino)-6-Methoxy-Quinoline-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex quinoline-based molecular architecture. This compound matters for its role as a critical building block in the synthesis of targeted therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D laboratories and fine chemical producers engaged in developing novel small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), especially kinase inhibitors.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Acts as a versatile building block for constructing complex heterocyclic compounds in organic and process chemistry.
• Biochemical Research: Employed as a tool compound or probe in biochemical assays to study specific biological pathways and target validation.
• Fine Chemical Production: Integral in the cGMP-compliant manufacturing of high-value, low-volume specialty chemicals for the life sciences industry.

Basic Information

Product Name	7-(3-Chloro-Propoxy)-4-(2,4-Dichloro-5-Methoxy-Phenylamino)-6-Methoxy-Quinoline-3-Carbonitrile
CAS No.	380844-49-5
Molecular Formula	C21H18Cl3N3O3
Molecular Weight	474.74 g/mol
Synonyms	4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-(3-chloropropoxy)-6-methoxyquinoline-3-carbonitrile; 7-(3-Chloropropoxy)-4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-3-quinolinecarbonitrile; 380844-49-5; Quinoline-3-carbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-(3-chloropropoxy)-6-methoxy-; 4-(2,4-Dichloro-5-methoxy-phenylamino)-7-(3-chloro-propoxy)-6-methoxy-quinoline-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 7-(3-Chloro-Propoxy)-4-(2,4-Dichloro-5-Methoxy-Phenylamino)-6-Methoxy-Quinoline-3-Carbonitrile is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and compliance documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.