Description

Dirhodium Tetrakis[n-Phthaloyl-(R)-tert-Leucinate] Bis(Ethyl Acetate) Adduct is a highly specialized chiral dirhodium(II) carboxylate catalyst, recognized for its exceptional enantioselectivity in asymmetric synthesis. This compound matters for its critical role in enabling high-value, stereocontrolled chemical transformations, offering researchers and manufacturers a reliable tool for constructing complex molecular architectures. It is primarily needed by pharmaceutical R&D teams, fine chemical producers, and academic laboratories focused on developing novel active pharmaceutical ingredients (APIs) and advanced organic intermediates.

Application

• Asymmetric C-H Functionalization: A premier catalyst for enantioselective insertion reactions into C-H bonds, enabling streamlined synthesis of chiral centers.
• Pharmaceutical Intermediate Synthesis: Critical for the production of enantiomerically pure intermediates in the development of new drugs, including antivirals and CNS-active compounds.
• Cyclopropanation Reactions: Used to catalyze the formation of chiral cyclopropane rings, key structural motifs in many bioactive molecules and agrochemicals.
• Academic & Process Chemistry Research: A staple catalyst in methodological development for novel asymmetric transformations in university and industrial R&D settings.
• Scale-up for Fine Chemical Production: Suitable for pilot-scale and commercial manufacturing of specialty chemicals where high enantiomeric excess (ee) is required.

Basic Information

Product Name	Dirhodium Tetrakis[n-Phthaloyl-(R)-tert-Leucinate] Bis(Ethyl Acetate) Adduct
CAS No.	380375-05-3
Molecular Formula	C68H68N4O20Rh2 • 2(C4H8O2)
Molecular Weight	Contact for details
Synonyms	Dirhodium(II) Tetrakis[(R)-N-phthaloyl-tert-leucinate]; Rh2(R-PTTL)4•2(EtOAc); Dirhodium(II) (R)-PTTL; [Rh2((R)-PTTL)4]; (R)-Dirhodium Tetrakis(phthaloyl-tert-leucinate); Dirhodium(II) Carboxylate Catalyst (R-PTTL); Dirhodium Tetrakis(N-phthaloyl-(R)-tert-leucinate) Bis(Acetate) Solvate
EINECS	Contact for details

Quality Control

Our Dirhodium Tetrakis[n-Phthaloyl-(R)-tert-Leucinate] Bis(Ethyl Acetate) Adduct is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by advanced analytical techniques, including NMR, HPLC, and elemental analysis, to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term stability, store under an inert atmosphere such as argon or nitrogen to prevent potential oxidation or moisture uptake. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Dark green to blue-green crystalline solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Rhodium Content	Contact for details
Solvent Content (Residual EtOAc)	≤ 2.0% (by 1H NMR)
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.