Description

4-(4-Difluoromethylsulfanyl-Phenyl)-5-Pyridin-3-Yl-4H-[1,2,4]Triazole-3-Thiol is a high-value, sulfur-containing heterocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring a triazole-thiol core linked to difluoromethylthio and pyridyl groups, makes it an essential building block for developing novel active ingredients. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting enzymes or receptors where the triazole-thiol moiety can act as a pharmacophore or metal-binding group.
• Agrochemical Research: Used in the development of new fungicides, herbicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Can be investigated as a monomer or additive for creating specialized polymers with unique electronic or adhesive properties.
• Ligand Synthesis: Serves as a starting material for synthesizing complex ligands used in catalysis and coordination chemistry.
• Chemical Biology Probe Development: Utilized in research to create molecular probes for studying biological processes due to its potential for selective binding.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise scaffold.

Basic Information

Product Name	4-(4-Difluoromethylsulfanyl-Phenyl)-5-Pyridin-3-Yl-4H-[1,2,4]Triazole-3-Thiol
CAS No.	380349-27-9
Molecular Formula	C15H10F2N4S2
Molecular Weight	348.39 g/mol
Synonyms	4-[4-(Difluoromethylthio)phenyl]-5-(3-pyridinyl)-4H-1,2,4-triazole-3-thiol; 5-(Pyridin-3-yl)-4-[4-(difluoromethylsulfanyl)phenyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione; 4-(4-(Difluoromethylthio)phenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol; 380349-27-9; 1,2,4-Triazole-3-thiol, 4-[4-(difluoromethylthio)phenyl]-5-(3-pyridinyl)-; SCHEMBL23305577; AKOS040750623; FT-0775787
EINECS	Contact for details

Quality Control

Our production of 4-(4-Difluoromethylsulfanyl-Phenyl)-5-Pyridin-3-Yl-4H-[1,2,4]Triazole-3-Thiol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity and quantify purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.