Description

1-(Piperidin-4-Yl)Hydrazine Dihydrochloride is a high-purity, versatile organic building block and key intermediate in advanced chemical synthesis. Its value lies in its bifunctional hydrazine and piperidine structure, enabling its use in the construction of complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those containing piperidine or hydrazine pharmacophores, such as kinase inhibitors, CNS-active compounds, and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators that require specific nitrogen-containing heterocycles.
• Chemical Research & Development: Serves as a versatile precursor in medicinal chemistry and process chemistry for constructing complex molecular architectures and exploring new synthetic routes.
• Ligand and Catalyst Preparation: Employed in the development of novel chiral ligands, metal-organic frameworks (MOFs), and catalysts for asymmetric synthesis and other catalytic processes.
• Material Science Precursor: Potential use in the synthesis of functional polymers, dyes, and other advanced materials where its diamine functionality can be incorporated.

Basic Information

Product Name	1-(Piperidin-4-Yl)Hydrazine Dihydrochloride
CAS No.	380226-98-2
Molecular Formula	C5H13N3 · 2HCl
Molecular Weight	209.11 g/mol
Synonyms	4-Hydrazinylpiperidine Dihydrochloride; 4-Hydrazinopiperidine Dihydrochloride; 1-(4-Piperidinyl)hydrazine Dihydrochloride; Piperidin-4-yl-hydrazine Dihydrochloride; 4-Piperidinylhydrazine Dihydrochloride; 1-(Piperidin-4-yl)hydrazine Dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Piperidin-4-Yl)Hydrazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and heavy metals to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.