Description

5-Amino-5,6,7,8-tetrahydro-2(1H)-quinolinone is a high-purity, advanced pharmaceutical intermediate with a unique tetrahydroquinolinone scaffold. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is essential for research and development teams in the pharmaceutical and agrochemical industries seeking to develop new therapeutic agents or crop protection products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection and pest management solutions.
• Organic Synthesis: Employed in academic and industrial laboratories for the construction of complex nitrogen-containing heterocycles.
• Biochemical Tool Compound: Potential use in developing probes for studying enzymatic pathways and biological targets.

Basic Information

Product Name	5-Amino-5,6,7,8-tetrahydro-2(1H)-quinolinone
CAS No.	380189-31-1
Molecular Formula	C9H12N2O
Molecular Weight	164.21 g/mol
Synonyms	5-Amino-1,2,3,4-tetrahydro-2-quinolinone; 5-Amino-5,6,7,8-tetrahydroquinolin-2(1H)-one; 2(1H)-Quinolinone, 5-amino-5,6,7,8-tetrahydro-; 5-Amino-1,2,3,4-tetrahydroquinolin-2-one; 5-Amino-2-oxo-1,2,3,4-tetrahydroquinoline; 5-Aminotetrahydro-2-quinolone
EINECS	Contact for details

Quality Control

Our 5-Amino-5,6,7,8-tetrahydro-2(1H)-quinolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.