Description

(R)-1-(4-Methoxyphenyl)Propan-1-Amine-Hcl CAS NO 379711-94-1 is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity and environmental safety.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require a specific (R)-enantiomer configuration.
• Academic & Industrial Research: A valuable reference standard and reagent in medicinal chemistry and process development laboratories for route scouting and optimization.

Basic Information

Product Name	(R)-1-(4-Methoxyphenyl)Propan-1-Amine Hydrochloride
CAS No.	379711-94-1
Molecular Formula	C10H16ClNO
Molecular Weight	201.69 g/mol
Synonyms	(R)-1-(4-Methoxyphenyl)propan-1-amine hydrochloride; (R)-1-(p-Methoxyphenyl)propylamine hydrochloride; (R)-4-Methoxy-α-methylbenzylamine hydrochloride; (R)-1-Amino-1-(4-methoxyphenyl)propane hydrochloride; (R)-p-Methoxyamphetamine hydrochloride; (R)-PMA HCl; (R)-1-(4-Methoxyphenyl)-1-aminopropane HCl
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Methoxyphenyl)Propan-1-Amine-Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and commercial use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (R-enantiomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.