Description

4(1H)-Quinazolinone, 5-Hydroxy-7-Methoxy- is a high-purity quinazolinone derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new compounds with targeted biological activities. Its specific substitution pattern offers a strategic handle for further functionalization.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex molecules in custom synthesis and contract manufacturing.
• Biochemical Tool Compound: Potential use in developing probes for studying biological mechanisms and cellular processes.

Basic Information

Item	Detail
Product Name	4(1H)-Quinazolinone, 5-Hydroxy-7-Methoxy-
CAS No.	379228-50-9
Molecular Formula	C9H8N2O3
Molecular Weight	192.17 g/mol
Synonyms	5-Hydroxy-7-methoxyquinazolin-4(1H)-one; 7-Methoxy-5-hydroxy-4(1H)-quinazolinone; 5-Hydroxy-7-methoxy-1,4-dihydroquinazolin-4-one; 4-Hydroxy-7-methoxyquinazoline; AQ-101 (research code); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4(1H)-Quinazolinone, 5-Hydroxy-7-Methoxy- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to ensure traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.