Description

3H-Pyrrolo[1,2-A]Azepin-3-One,5,6,9,9A-Tetrahydro-,(9Ar)-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. Research and development teams in the pharmaceutical and biotechnology sectors need this precise chemical scaffold to explore new therapeutic pathways and develop next-generation medications.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Serves as a versatile core structure for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Used in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) requiring a pyrroloazepinone moiety.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	3H-Pyrrolo[1,2-A]Azepin-3-One,5,6,9,9A-Tetrahydro-,(9Ar)-(9Ci)
CAS No.	378248-25-0
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(9aR)-5,6,9,9a-Tetrahydro-3H-pyrrolo[1,2-a]azepin-3-one; (9aR)-3H-Pyrrolo[1,2-a]azepin-3-one, 5,6,9,9a-tetrahydro-; Tetrahydro-3H-pyrrolo[1,2-a]azepin-3-one (9aR)-; Pyrroloazepinone derivative; Fused bicyclic lactam; Advanced pharmaceutical intermediate (API Intermediate)
EINECS	Contact for details

Quality Control

Every batch of 3H-Pyrrolo[1,2-A]Azepin-3-One,5,6,9,9A-Tetrahydro-,(9Ar)-(9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request and can support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.