Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxamide, n-Hydroxy- (9Ci) is a specialized bicyclic organic compound featuring a reactive norbornene core and a hydroxamic acid functional group. This unique molecular architecture makes it a valuable high-purity building block and intermediate for advanced chemical synthesis. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Chemical Biology Probe: Used in research to develop activity-based probes for studying metalloenzymes like matrix metalloproteinases (MMPs) and histone deacetylases (HDACs).
• Ligand Synthesis: Acts as a starting material for creating chelating agents and ligands in coordination chemistry and catalysis.
• Polymer Science: Utilized in the development of specialty polymers and functional materials via its norbornene moiety, which can undergo ring-opening metathesis polymerization (ROMP).
• Agrochemical Research: Employed in the discovery and development of new crop protection agents with specific modes of action.
• Academic & Industrial R&D: A critical reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxamide, n-Hydroxy- (9Ci)
CAS No.	377074-31-2
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	N-Hydroxybicyclo[2.2.1]hept-5-ene-2-carboxamide; 5-Norbornene-2-carbohydroxamic acid; N-Hydroxy-5-norbornene-2-carboxamide; Bicyclo[2.2.1]hept-5-ene-2-carbohydroxamic acid; 2-Norbornenecarbohydroxamic acid, N-Hydroxy-; N-Hydroxynorborn-5-ene-2-carboxamide; 5-Norbornene-2-carboxylic acid hydroxamide
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Hept-5-Ene-2-Carboxamide, n-Hydroxy- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.