Description

2-Chloro-1-(6-Methoxy-2,2,4-Trimethyl-3,4-Dihydro-2H-Quinolin-1-Yl)-Ethanone is a specialized organic intermediate featuring a dihydroquinoline core structure. This compound is valued for its role as a key building block in the synthesis of complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors for constructing novel drug candidates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential therapeutic agents, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Chemistry: Serves as a monomer or functionalizing agent in the research of advanced organic materials, such as dyes or photoactive compounds.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions involving chlorinated ketones and dihydroquinolines.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds and bespoke chemical entities for client-specific projects.

Basic Information

Product Name	2-Chloro-1-(6-Methoxy-2,2,4-Trimethyl-3,4-Dihydro-2H-Quinolin-1-Yl)-Ethanone
CAS No.	376371-15-2
Molecular Formula	C₁₅H₁₈ClNO₂
Molecular Weight	279.76 g/mol
Synonyms	1-(2-Chloroacetyl)-6-methoxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline; 2-Chloro-1-(6-methoxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-1-yl)ethanone; 6-Methoxy-2,2,4-trimethyl-1-(2-chloroacetyl)-1,2,3,4-tetrahydroquinoline; 1-(Chloroacetyl)-6-methoxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline; Tetrahydroquinoline chloroacetyl derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(6-Methoxy-2,2,4-Trimethyl-3,4-Dihydro-2H-Quinolin-1-Yl)-Ethanone is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.