Description

1H-Pyrrolizine-7A(5H)-Carboxylicacid,2-Aminotetrahydro-3-Oxo-,Methylester is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a critical, structurally complex scaffold for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create innovative molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides that require specific heterocyclic motifs for bioactivity.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for creating molecular probes, enzyme inhibitors, or tool compounds in biochemical research.
• Material Science: Potential building block for advanced organic electronic materials or specialty polymers due to its fused ring system and functional groups.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic methodology and medicinal chemistry projects.
• Custom Synthesis & Scale-Up: A critical starting material for custom synthesis houses offering contract manufacturing services for complex, low-volume specialty chemicals.

Basic Information

Product Name	1H-Pyrrolizine-7A(5H)-Carboxylicacid,2-Aminotetrahydro-3-Oxo-,Methylester
CAS No.	375792-70-4
Molecular Formula	C9H12N2O3
Molecular Weight	196.20 g/mol
Synonyms	Methyl 2-amino-3-oxo-2,3,5,7a-tetrahydro-1H-pyrrolizine-7a-carboxylate; 2-Aminotetrahydro-3-oxo-1H-pyrrolizine-7a(5H)-carboxylic acid methyl ester; 1H-Pyrrolizine-7a(5H)-carboxylic acid, 2-amino-2,3,5,7a-tetrahydro-3-oxo-, methyl ester; 7a-Methoxycarbonyl-2-amino-2,3,5,7a-tetrahydro-1H-pyrrolizin-3-one; Pyrrolizine carboxylate derivative CAS 375792-70-4
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolizine-7A(5H)-Carboxylicacid,2-Aminotetrahydro-3-Oxo-,Methylester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive compound from humidity. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.