Description

3-(Benzyloxy)-2-Hydroxypropanoic Acid is a versatile chiral building block and synthetic intermediate of significant value in fine chemical synthesis. Its structure, featuring both a protected hydroxyl group and a carboxylic acid functionality, makes it a critical precursor for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key starting material or chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic or inflammatory pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Polymer Modification: Employed in the synthesis of functional monomers or as a modifier to introduce benzyl-protected hydroxyl and carboxylic acid groups into polymer chains.
• Peptidomimetic Research: Useful in medicinal chemistry for the design and synthesis of peptide analogs and mimetics to improve metabolic stability.
• Fine Chemical Production: A valuable intermediate in multi-step organic synthesis for creating complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	3-(Benzyloxy)-2-Hydroxypropanoic Acid
CAS No.	374936-90-0
Molecular Formula	C10H12O4
Molecular Weight	196.20 g/mol
Synonyms	2-Hydroxy-3-(phenylmethoxy)propanoic Acid; (R/S)-3-(Benzyloxy)-2-hydroxypropanoic Acid; DL-3-Benzyloxy-2-hydroxypropionic Acid; 3-Benzyloxy-2-hydroxypropionic Acid; 3-(Benzyloxy)-2-hydroxypropionic Acid; α-Hydroxy-β-(benzyloxy)propionic Acid; Benzyl Glycidate Hydrolysis Derivative
EINECS	Contact for details

Quality Control

Our 3-(Benzyloxy)-2-Hydroxypropanoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.