Description

3-Bromo-5-(4-Fluorophenoxy)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorophenoxy moiety contributes to biological activity.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-5-(4-Fluorophenoxy)Pyridine
CAS No.	374935-03-2
Molecular Formula	C11H7BrFNO
Molecular Weight	268.08 g/mol
Synonyms	5-Bromo-3-(4-fluorophenoxy)pyridine; 3-Bromo-5-(p-fluorophenoxy)pyridine; Pyridine, 3-bromo-5-(4-fluorophenoxy)-; 374935-03-2; 3-Br-5-(4-F-PhO)-Pyridine; 3-Bromo-5-(4-fluorophenoxy)pyridin; 3-Bromo-5-(4'-fluorophenoxy)pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-(4-Fluorophenoxy)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and GC-MS are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.