Description

3-(4-Bromo-1-Naphthyl)-3-Oxopropanenitrile is a specialized brominated naphthalene derivative that serves as a high-value synthetic intermediate. Its molecular structure, featuring both a bromo-substituted naphthalene ring and a reactive cyanoacetyl group, makes it a versatile building block for constructing complex organic frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in display and lighting technologies.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Intermediate for developing new generation herbicides and plant growth regulators with novel modes of action.
• Dye and Pigment Chemistry: Core structure for synthesizing advanced colorants and functional dyes with specific light-absorption properties.
• Academic & Contract Research: Essential reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	3-(4-Bromo-1-Naphthyl)-3-Oxopropanenitrile
CAS No.	374926-06-4
Molecular Formula	C₁₃H₈BrNO
Molecular Weight	274.11 g/mol
Synonyms	4-Bromo-1-cyanoacetylnaphthalene; 4'-Bromo-1'-naphthyl cyanoacetate; 3-Oxo-3-(4-bromonaphthalen-1-yl)propanenitrile; (4-Bromo-1-naphthoyl)acetonitrile; 1-(4-Bromo-1-naphthyl)-1,3-butanedione nitrile; Cyano(4-bromo-1-naphthoyl)methane; Propanenitrile, 3-(4-bromo-1-naphthalenyl)-3-oxo-
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Bromo-1-Naphthyl)-3-Oxopropanenitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and process-scale applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting purity, identity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.