Description

2-Oxa-7-Azaspiro[4.5]Decane, Hydrochloride (1:1) is a high-purity, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and structurally constrained scaffold, enabling the development of novel molecules with specific three-dimensional properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of complex active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS).
• Medicinal Chemistry Scaffold: Used as a constrained heterocyclic core for constructing compound libraries in hit-to-lead and lead optimization programs.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products.
• Chemical Biology Probe Synthesis: Utilized to create tool compounds for studying biological pathways and protein function.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in organic and heterocyclic chemistry.
• Process Chemistry Development: Investigated for scalable synthetic routes in pilot plant and commercial manufacturing settings.

Basic Information

Product Name	2-Oxa-7-Azaspiro[4.5]Decane, Hydrochloride (1:1)
CAS No.	374795-37-6
Molecular Formula	C8H15NO·HCl
Molecular Weight	177.67 g/mol
Synonyms	7-Aza-2-oxaspiro[4.5]decane hydrochloride; 2-Oxa-7-azaspiro[4.5]decane hydrochloride; 1-Oxa-4-azaspiro[4.5]decane hydrochloride (alternative numbering); 7-Aza-2-oxaspiro[4.5]decane HCl; Spiro[4.5]decane, 2-oxa-7-aza-, hydrochloride; 374795-37-6; 2-Oxa-7-azaspiro[4.5]decan-7-ium chloride
EINECS	Contact for details

Quality Control

Our 2-Oxa-7-Azaspiro[4.5]Decane, Hydrochloride (1:1) is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.