Description

Diacetato[(R)-(+)-2,2'-Bis(Diphenylphosphino)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthy]Ruthenium(II) is a high-performance, chiral ruthenium complex widely recognized for its exceptional catalytic activity in asymmetric hydrogenation and other enantioselective transformations. This compound matters because it enables the precise synthesis of chiral molecules, which are critical for developing pharmaceuticals, agrochemicals, and advanced materials with high optical purity. It is an essential tool for research chemists and process development scientists in the pharmaceutical, fine chemical, and academic sectors who require reliable and efficient catalysts for creating single-enantiomer products.

Application

• Asymmetric Hydrogenation Catalyst: A premier catalyst for the enantioselective reduction of functionalized olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Critical for the production of chiral active pharmaceutical ingredients (APIs), including β-amino acids, lactams, and other complex heterocycles.
• Fine Chemical Manufacturing: Used in the synthesis of high-value chiral compounds for agrochemicals, flavors, and fragrances.
• Academic & Process Research: A valuable reagent for methodology development and studying mechanisms in asymmetric catalysis and organometallic chemistry.
• Chiral Ligand Precursor: Serves as a source for generating other active ruthenium catalytic species in situ for various coupling and isomerization reactions.

Basic Information

Product Name	Diacetato[(R)-(+)-2,2'-Bis(Diphenylphosphino)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthy]Ruthenium(II)
CAS No.	374067-51-3
Molecular Formula	C48H46O4P2Ru
Molecular Weight	863.89 g/mol
Synonyms	(R)-Ru(OAc)2(H8-BINAP); (R)-H8-BINAP-Ru(OAc)2; Ruthenium(II) acetate (R)-H8-BINAP complex; (R)-(+)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl diacetato ruthenium(II); (R)-H8-BINAP-Ru diacetate; Ru(H8-binap)(OAc)2; (R)-OctahydroBINAP-Ru(OAc)2; Asymmetric hydrogenation catalyst Ru(H8-BINAP)(OAc)2
EINECS	Contact for details

Quality Control

Our Diacetato[(R)-(+)-H8-BINAP]Ruthenium(II) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analysis, including HPLC purity assessment, chiral purity verification, and residual solvent analysis. A detailed Certificate of Analysis (COA) providing full specifications is supplied with every shipment. We support development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C for long-term stability. The material is sensitive to moisture and air. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Ruthenium Content	11.5 - 12.2 %
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.