Description

4,4'-Dichloro-3,3'-Bis(trifluoromethyl)-1,1'-biphenyl is a specialized fluorinated biphenyl derivative, recognized for its unique structural properties. This compound matters as a high-value advanced pharmaceutical intermediate and a key building block in the synthesis of complex organic molecules. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Serves as a key building block for novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl groups.
• Liquid Crystal Materials: Used in the research and development of fluorinated liquid crystals for advanced display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a core or dopant material in the development of electron-transport or host layers for OLED devices.
• Polymer Modification: Employed to introduce fluorinated biphenyl units into polymer backbones to enhance thermal stability, chemical resistance, and optical properties.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Material Science Research: Used in academic and industrial R&D for creating novel organic semiconductors and porous framework materials.

Basic Information

Product Name	4,4'-Dichloro-3,3'-Bis(trifluoromethyl)-1,1'-Biphenyl
CAS No.	372956-43-9
Molecular Formula	C14H6Cl2F6
Molecular Weight	359.10 g/mol
Synonyms	3,3'-Bis(trifluoromethyl)-4,4'-dichlorobiphenyl; 4,4'-Dichloro-3,3'-bis(trifluoromethyl)biphenyl; 1,1'-Biphenyl, 4,4'-dichloro-3,3'-bis(trifluoromethyl)-; 3,3',4,4'-Tetrasubstituted Biphenyl Derivative; DCBTFB; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our 4,4'-Dichloro-3,3'-Bis(trifluoromethyl)-1,1'-Biphenyl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.