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Benzoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-3-Methoxy- (9Ci) CAS NO 372144-26-8


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CAS No.:372144-26-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Benzoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-3-Methoxy- (9Ci) is a specialized, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in facilitating complex, multi-step reactions where selective protection and deprotection of functional groups are required. It is primarily needed by research chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for the synthesis of peptides, peptidomimetics, and other bioactive molecules.

Application

  • Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid derivative for the controlled assembly of peptide chains.
  • Pharmaceutical Intermediate: A key precursor in the research and development of novel active pharmaceutical ingredients (APIs) and drug candidates.
  • Bioconjugation Chemistry: Used in the synthesis of linker molecules for antibody-drug conjugates (ADCs) and other targeted therapies.
  • Combinatorial Chemistry Libraries: Serves as a building block for generating diverse compound libraries for high-throughput screening.
  • Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators.
  • Material Science: A monomer or modifier in the development of specialized polymers and functional materials.

Basic Information

Product Name Benzoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-3-Methoxy- (9Ci)
CAS No. 372144-26-8
Molecular Formula C24H21NO6
Molecular Weight 419.43 g/mol
Synonyms Fmoc-3-methoxytyrosine; Fmoc-O-methyl-L-tyrosine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyl-L-tyrosine; 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-methoxybenzoic acid; Fmoc-Tyr(Me)-OH; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(3-methoxyphenyl)propanoic acid; Fmoc-O-Me-Tyr-OH; N-α-Fmoc-O-methyl-L-tyrosine
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Quality Control

Our Benzoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-3-Methoxy- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Specific Rotation -15.0° to -20.0° (c=1 in DMF)
Water Content (KF) ≤ 0.5%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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