Description

3-(4-Oxo-3,4-Dihydroquinazolin-2-Yl)Phenyl Acetate is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, where precise chemical structure and purity are paramount for efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazolinone-based drug candidates for oncology and other therapeutic areas.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a versatile scaffold for further functionalization to create libraries of compounds for biological screening.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-(4-Oxo-3,4-Dihydroquinazolin-2-Yl)Phenyl Acetate
CAS No.	371947-93-2
Molecular Formula	C16H12N2O3
Molecular Weight	280.28 g/mol
Synonyms	2-(3-Acetoxyphenyl)-3,4-dihydro-4-quinazolinone; 2-(3-Acetoxyphenyl)-4(3H)-quinazolinone; 3-(4-Oxo-3,4-dihydroquinazolin-2-yl)phenyl acetate; 2-(3-Hydroxyphenyl)-4(3H)-quinazolinone acetate; Quinazolinone derivative 371947-93-2; [3-(4-Oxo-3,4-dihydroquinazolin-2-yl)phenyl] acetate
EINECS	Contact for details

Quality Control

Our 3-(4-Oxo-3,4-Dihydroquinazolin-2-Yl)Phenyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.