Description

Furo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Amino-, Ethyl Ester (9Ci) is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its fused furopyridine structure, which serves as a privileged scaffold for developing novel pharmacologically active compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating new molecules with potential biological activity. Its defined structure and functional groups allow for precise derivatization in complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, or oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein interactions.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components for organic electronics.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	Furo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Amino-, Ethyl Ester (9Ci)
CAS No.	371945-06-1
Molecular Formula	C11H10N2O3
Molecular Weight	218.21 g/mol
Synonyms	3-Aminofuro[2,3-b]pyridine-2-carboxylic acid ethyl ester; Ethyl 3-amino-2-furo[2,3-b]pyridinecarboxylate; 3-Amino-2-ethoxycarbonylfuro[2,3-b]pyridine; Ethyl 3-aminofuro[2,3-b]pyridine-2-carboxylate; 2-Carbethoxy-3-amino-furo[2,3-b]pyridine; 371945-06-1; Furo[2,3-b]pyridine-2-carboxylic acid, 3-amino-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of Furo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Amino-, Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and scale-up projects with customized purity grades to meet specific research and cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.