Description

6-Bromo-2-(2,5-Dimethyl-Phenyl)-Quinoline-4-Carboxylic Acid is a high-purity, functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other biological pathways where the quinoline core is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its halogenated aromatic structure for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, or metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a molecular probe or a tag in bioconjugation chemistry due to its reactive carboxylic acid and bromo functional groups.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-2-(2,5-Dimethyl-Phenyl)-Quinoline-4-Carboxylic Acid
CAS No.	371136-06-0
Molecular Formula	C18H14BrNO2
Molecular Weight	356.22 g/mol
Synonyms	6-Bromo-2-(2,5-dimethylphenyl)quinoline-4-carboxylic acid; 2-(2,5-Dimethylphenyl)-6-bromoquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-bromo-2-(2,5-dimethylphenyl)-; 6-Bromo-2-(2,5-xylyl)quinoline-4-carboxylic acid; Quinoline-4-carboxylic acid, 6-bromo-2-(2,5-dimethylphenyl)-; BRD-K4477; CAS 371136-06-0
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(2,5-Dimethyl-Phenyl)-Quinoline-4-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.