Description

2,6,8-Trimethyl-3-[(4-Methyl-1-Piperazinyl)Methyl]-4-Quinolinol is a specialized quinoline derivative with a piperazine-containing side chain, representing a high-value synthetic intermediate in advanced organic synthesis. This compound matters for its role as a key building block in the research and development of novel pharmacologically active molecules, particularly in medicinal chemistry. It is needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents, especially within the fields of oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize drug-like properties.
• Chemical Biology Probe Development: Employed in the creation of molecular probes to study enzyme function or protein interactions in biological systems.
• High-Throughput Screening (HTS): Included in specialized compound libraries for screening against novel therapeutic targets.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke, complex molecules for client-specific research programs.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and synthetic methodology development.

Basic Information

Item	Detail
Product Name	2,6,8-Trimethyl-3-[(4-Methyl-1-Piperazinyl)Methyl]-4-Quinolinol
CAS No.	371117-20-3
Molecular Formula	C₁₈H₂₅N₃O
Molecular Weight	299.41 g/mol
Synonyms	3-[(4-Methylpiperazin-1-yl)methyl]-2,6,8-trimethylquinolin-4-ol; 2,6,8-Trimethyl-3-[(4-methyl-1-piperazinyl)methyl]-4(1H)-quinolinone (tautomer); 4-Quinolinol, 2,6,8-trimethyl-3-[(4-methyl-1-piperazinyl)methyl]-; 371117-20-3; 4-Hydroxy-2,6,8-trimethyl-3-(4-methylpiperazin-1-ylmethyl)quinoline
EINECS	Contact for details

Quality Control

Our 2,6,8-Trimethyl-3-[(4-Methyl-1-Piperazinyl)Methyl]-4-Quinolinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.