Description

(2R)-5-Bromo-2,3-Dihydro-1H-Inden-2-Ylamine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders. It is primarily required by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel therapeutic candidates. The hydrochloride salt form offers enhanced stability and handling properties for precise synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in neuroscience.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for potential CNS-active molecules.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and commercial route development for APIs.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block to introduce stereochemical complexity into target molecules.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Used in university and institutional labs for studying synthetic methodologies and pharmacological mechanisms.

Basic Information

Product Name	(2R)-5-Bromo-2,3-Dihydro-1H-Inden-2-Ylamine Hydrochloride
CAS No.	370861-59-9
Molecular Formula	C9H11BrClN
Molecular Weight	248.55 g/mol
Synonyms	(2R)-5-Bromo-2-aminoindane hydrochloride; (R)-5-Bromo-2,3-dihydro-1H-inden-2-amine hydrochloride; (R)-5-Bromo-2-aminoindane HCl; 5-Bromo-(2R)-2,3-dihydro-1H-inden-2-amine hydrochloride; (2R)-5-Bromoindan-2-amine hydrochloride; (R)-5-Bromo-2-indanamine hydrochloride; 370861-59-9; (2R)-5-Bromo-1H-inden-2-amine hydrochloride
EINECS	Contact for details

Quality Control

Our (2R)-5-Bromo-2,3-Dihydro-1H-Inden-2-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.