Description

4-(cis-4-Hydroxycyclohexyl)Phenol is a versatile bifunctional organic intermediate featuring both phenolic and alicyclic hydroxyl groups. This compound matters for its unique structural motif, which enables its use in the synthesis of advanced materials and fine chemicals requiring specific stereochemistry and dual reactivity. Industries such as pharmaceuticals, liquid crystal polymers, and specialty polymer manufacturing need this high-purity building block to develop novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and hormone-related therapies.
• Liquid Crystal Monomer: Serves as a core component in the synthesis of monomers for liquid crystal polymers (LCPs) and displays, contributing to thermal stability and optical performance.
• Polymer Modifier: Used to introduce hydroxyl functionality into polymer backbones, enhancing adhesion, cross-linking potential, and compatibility in high-performance epoxy and polyurethane systems.
• Advanced Material Synthesis: Employed in R&D for creating novel organic frameworks, dendrimers, and other structured materials where precise spatial orientation of functional groups is critical.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for exploring new organic reactions and catalytic processes involving sterically defined diols/phenols.

Basic Information

Product Name	4-(cis-4-Hydroxycyclohexyl)Phenol
CAS No.	370860-74-5
Molecular Formula	C12H16O2
Molecular Weight	192.25 g/mol
Synonyms	4-(4-Hydroxycyclohexyl)phenol (cis-isomer); cis-4-(4-Hydroxyphenyl)cyclohexanol; 4-Hydroxycyclohexylphenol; p-(cis-4-Hydroxycyclohexyl)phenol; 1,1'-Biphenyl-4-ol, 4'-cyclohexyl- (cis); 4-(cis-Hydroxycyclohexyl)phenol; Phenol, 4-(4-hydroxycyclohexyl)-, cis-
EINECS	Contact for details

Quality Control

Our production of 4-(cis-4-Hydroxycyclohexyl)Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed against comprehensive specifications using advanced analytical techniques such as HPLC, GC, and NMR. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
cis-Isomer Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.