Description

4-(((2,4-Dioxo-1,5-Dioxaspiro[5.5]Undecan-3-Ylidene)Methyl)Amino)Benzenesulfonamide is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new drug candidates, especially in oncology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules and investigational new drugs (INDs).
• Organic Synthesis Building Block: Used in research-scale organic chemistry for constructing spirocyclic and heterocyclic frameworks.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Bioconjugation Chemistry: Potential use in developing antibody-drug conjugates (ADCs) or other targeted therapies due to its reactive functional groups.

Basic Information

Item	Details
Product Name	4-(((2,4-Dioxo-1,5-Dioxaspiro[5.5]Undecan-3-Ylidene)Methyl)Amino)Benzenesulfonamide
CAS No.	370853-58-0
Molecular Formula	C17H18N2O5S
Molecular Weight	362.40 g/mol
Synonyms	4-[(2,4-Dioxo-1,5-dioxaspiro[5.5]undec-3-ylidene)methylamino]benzenesulfonamide; 4-[[(2,4-Dioxo-1,5-dioxaspiro[5.5]undec-3-ylidene)methyl]amino]benzenesulfonamide; Benzenesulfonamide, 4-(((2,4-dioxo-1,5-dioxaspiro[5.5]undec-3-ylidene)methyl)amino)-; Spirocyclic Sulfonamide Intermediate; 1,5-Dioxaspiro[5.5]undecane-3-carboxaldehyde, 2,4-dioxo-, 4-aminobenzenesulfonamide derivative
EINECS	Contact for details

Quality Control

Our production of 4-(((2,4-Dioxo-1,5-Dioxaspiro[5.5]Undecan-3-Ylidene)Methyl)Amino)Benzenesulfonamide adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.