Description

6-Methyl-5-Nitro-2-(Trifluoromethyl)Chromen-4-One is a high-purity, fluorinated chromenone derivative, a key synthetic intermediate in advanced organic chemistry. Its value lies in its unique trifluoromethyl and nitro-substituted chromone scaffold, which is crucial for imparting specific bioactivity and physicochemical properties to target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly for anti-inflammatory, anticancer, and antimicrobial applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science: Acts as a precursor for organic electronic materials, dyes, and photoactive compounds due to its conjugated chromone core.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthetic chemistry projects.

Basic Information

Product Name	6-Methyl-5-Nitro-2-(Trifluoromethyl)Chromen-4-One
CAS No.	369631-68-5
Molecular Formula	C₁₂H₆F₃NO₄
Molecular Weight	285.18 g/mol
Synonyms	6-Methyl-5-nitro-2-(trifluoromethyl)-4H-chromen-4-one; 5-Nitro-6-methyl-2-(trifluoromethyl)-4H-1-benzopyran-4-one; 2-(Trifluoromethyl)-6-methyl-5-nitro-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 6-methyl-5-nitro-2-(trifluoromethyl)-; 369631-68-5; 6-Methyl-5-nitro-2-trifluoromethylchromone
EINECS	Contact for details

Quality Control

Our 6-Methyl-5-Nitro-2-(Trifluoromethyl)Chromen-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO principles ensures reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.