Description

2-(tert-Butoxycarbonyl)-2-(3,5-Dichlorophenyl)Acetic Acid is a high-purity, protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing substituted phenylacetic acid motifs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative for introducing specific functionalized side chains.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke intermediates for clients.

Basic Information

Item	Details
Product Name	2-(tert-Butoxycarbonyl)-2-(3,5-Dichlorophenyl)Acetic Acid
CAS No.	369403-30-5
Molecular Formula	C₁₃H₁₄Cl₂O₄
Molecular Weight	305.16 g/mol
Synonyms	Boc-3,5-Dichloro-DL-phenylglycine; N-Boc-2-(3,5-dichlorophenyl)glycine; 2-[(tert-Butoxycarbonyl)amino]-2-(3,5-dichlorophenyl)acetic acid; (3,5-Dichlorophenyl)((tert-butoxycarbonyl)amino)acetic acid; N-(tert-Butoxycarbonyl)-3,5-dichlorophenylglycine; Boc-DL-3,5-dichloro-Phe-OH; tert-Butyl (3,5-dichloro-2-carboxyphenyl)carbamate (tautomeric form); 369403-30-5
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxycarbonyl)-2-(3,5-Dichlorophenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.