Description

1-(1,1-Difluoro-2-Hydroxy-2-Phenyl-Ethyl)-4-Dimethylamino-Pyridinium Bromide is a high-purity, specialized organic salt with significant utility in advanced synthetic chemistry. This compound matters as a versatile building block and reagent, particularly valued for introducing functionalized fluorinated moieties into complex molecular architectures. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially those requiring fluorinated phenyl ethanolamine structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the difluoro-hydroxy-phenyl group confers specific biological activity and stability.
• Organic Synthesis Reagent: Acts as a fluorinating agent or a protected intermediate in multi-step synthetic routes for complex organic molecules.
• Ligand and Catalyst Precursor: Utilized in the preparation of specialized ligands for catalysis or as a precursor for pyridinium-based ionic liquids.
• Material Science Research: Employed in the development of novel fluorinated polymers or organic electronic materials.
• Academic & Industrial R&D: A critical tool for methodological development and exploring new chemical spaces in fluoroorganic chemistry.

Basic Information

Product Name	1-(1,1-Difluoro-2-Hydroxy-2-Phenyl-Ethyl)-4-Dimethylamino-Pyridinium Bromide
CAS No.	368873-76-1
Molecular Formula	C₁₆H₁₉BrF₂N₂O
Molecular Weight	373.24 g/mol
Synonyms	4-(Dimethylamino)-1-[1,1-difluoro-2-hydroxy-2-phenylethyl]pyridinium Bromide; N,N-Dimethyl-4-[(1,1-difluoro-2-hydroxy-2-phenylethyl)amino]pyridinium Bromide; 1-(1,1-Difluoro-2-hydroxy-2-phenylethyl)-4-(dimethylamino)pyridinium Bromide; 4-Dimethylamino-1-(1,1-difluoro-2-hydroxy-2-phenylethyl)pyridinium Bromide; DFHP-DMAP Bromide; Pyridinium, 4-(dimethylamino)-1-[1,1-difluoro-2-hydroxy-2-phenylethyl]-, bromide (1:1)
EINECS	Contact for details

Quality Control

Our 1-(1,1-Difluoro-2-Hydroxy-2-Phenyl-Ethyl)-4-Dimethylamino-Pyridinium Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.