Description

1-Difluoromethyl-4-Dimethylamino-Pyridinium Bromide is a specialized organic salt featuring a reactive pyridinium core with difluoromethyl and dimethylamino substituents. This compound matters as a versatile and highly reactive intermediate, particularly valuable for introducing the difluoromethyl group into complex molecules, a key modification in modern pharmaceutical and agrochemical design. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring difluoromethyl motifs to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the difluoromethyl group can enhance biological activity and environmental profile.
• Organic Synthesis Reagent: Acts as a potent electrophilic difluoromethylating agent in nucleophilic substitution and cross-coupling reactions.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in medicinal chemistry for labeling and probing biological targets and pathways.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial production of fine chemicals.

Basic Information

Product Name	1-Difluoromethyl-4-Dimethylamino-Pyridinium Bromide
CAS No.	368873-75-0
Molecular Formula	C9H13BrF2N2
Molecular Weight	267.12 g/mol
Synonyms	4-(Dimethylamino)-1-(difluoromethyl)pyridin-1-ium bromide; N,N-Dimethyl-4-[(difluoromethyl)amino]pyridinium bromide; 1-(Difluoromethyl)-4-(dimethylamino)pyridinium bromide; Difluoromethyl-dimethylaminopyridinium bromide; 4-Dimethylamino-1-difluoromethylpyridinium bromide; N-Difluoromethyl-N,N-dimethyl-4-aminopyridinium bromide
EINECS	Contact for details

Quality Control

Our 1-Difluoromethyl-4-Dimethylamino-Pyridinium Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.