Description

2-(4-Oxo-3,4-Dihydro-2-Quinazolinyl)-3-(2-Thienyl)Acrylonitrile is a high-value, heterocyclic organic compound featuring a quinazolinone core linked to a thiophene-acrylonitrile moiety. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active compounds. The compound, with CAS No. 367279-04-7, is supplied to meet the stringent purity and consistency requirements of modern drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Acts as a building block for novel crop protection agents and pesticides due to its bioactive heterocyclic structure.
• Organic Synthesis: Employed in academic and industrial research for developing novel synthetic methodologies involving quinazolinone and thiophene chemistry.
• Biochemical Tool Compound: Potential use in probing biological pathways and enzyme functions in biochemical assays.

Basic Information

Product Name	2-(4-Oxo-3,4-Dihydro-2-Quinazolinyl)-3-(2-Thienyl)Acrylonitrile
CAS No.	367279-04-7
Molecular Formula	C₁₅H₉N₃OS
Molecular Weight	279.32 g/mol
Synonyms	2-(4-Oxo-3,4-dihydroquinazolin-2-yl)-3-(thiophen-2-yl)acrylonitrile; 3-(2-Thienyl)-2-(4-oxo-3,4-dihydro-2-quinazolinyl)-2-propenenitrile; (2E)-2-(4-Oxo-3,4-dihydroquinazolin-2-yl)-3-(thiophen-2-yl)prop-2-enenitrile; Quinazolinone-thiophene acrylonitrile derivative; CAS 367279-04-7
EINECS	Contact for details

Quality Control

Our production of 2-(4-Oxo-3,4-Dihydro-2-Quinazolinyl)-3-(2-Thienyl)Acrylonitrile adheres to strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to minimize moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.