Description

4-Ethynyl-2-Hydroxy-Phenol is a versatile phenolic compound featuring both an ethynyl and a hydroxyl functional group on an aromatic ring. This unique bifunctional structure makes it a valuable advanced intermediate for synthesizing complex organic molecules, particularly in pharmaceutical and material science research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring alkyne functionality for click chemistry or coupling reactions.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators where the phenolic and ethynyl groups contribute to biological activity.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers, resins, and advanced materials with tailored thermal or mechanical properties.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized as a probe or tag in bioconjugation and labeling studies due to its reactive ethynyl group.
• Organic Electronic Materials: Investigated as a precursor for organic semiconductors and conductive polymers.

Basic Information

Product Name	4-Ethynyl-2-Hydroxy-Phenol
CAS No.	366808-04-0
Molecular Formula	C8H6O2
Molecular Weight	134.13 g/mol
Synonyms	4-Ethynylbenzene-1,2-diol; 4-Ethynylcatechol; 2-Hydroxy-4-ethynylphenol; 1,2-Dihydroxy-4-ethynylbenzene; 4-Ethynyl-1,2-benzenediol; 4-Ethynylpyrocatechol; 4-Ethynyl-2-hydroxyphenol; 4-Ethynylbenzenediol
EINECS	Contact for details

Quality Control

Our 4-Ethynyl-2-Hydroxy-Phenol is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent oxidation.

Specification

Item	Specification
Appearance	Off-white to light brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.