Description

2-([1,3]Dioxolo[4,5-G]Isoquinolin-8-Yl)Acetic Acid is a specialized heterocyclic acetic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique fused isoquinoline-dioxole structure makes it a valuable building block for the development of novel pharmacologically active compounds. This high-purity intermediate is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of complex molecules for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential therapeutic agents, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Building block for constructing complex heterocyclic scaffolds in structure-activity relationship (SAR) studies.
• Alkaloid Analog Synthesis: Used in the preparation of synthetic analogs of natural isoquinoline alkaloids for biological evaluation.
• Ligand Development: Serves as a core structure for developing novel ligands in biochemical and pharmacological assays.
• Advanced Material Synthesis: Potential monomer or precursor for creating specialized organic materials with specific electronic or photonic properties.
• Academic & Industrial R&D: Essential reagent for exploratory synthetic chemistry in both university laboratories and corporate R&D facilities.

Basic Information

Product Name	2-([1,3]Dioxolo[4,5-G]Isoquinolin-8-Yl)Acetic Acid
CAS No.	366446-04-0
Molecular Formula	C₁₃H₉NO₄
Molecular Weight	243.22 g/mol
Synonyms	2-(1,3-Dioxolo[4,5-g]isoquinolin-8-yl)acetic acid; 8-Carboxymethyl-1,3-dioxolo[4,5-g]isoquinoline; (1,3-Dioxolo[4,5-g]isoquinolin-8-yl)acetic acid; 2-(1,3-Dioxolo[4,5-g]isoquinolin-8-yl)ethanoic acid; 366446-04-0; AI3-52312; CTK8G0135; NSC-759841; ZINC000004054756
EINECS	Contact for details

Quality Control

Our production of 2-([1,3]Dioxolo[4,5-G]Isoquinolin-8-Yl)Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods for structural confirmation. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.