Description

3-Quinolinecarbonitrile, 1,4-Dihydro-7-Nitro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate characterized by its specific quinoline-based heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex bioactive molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and anti-infective research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex nitrogen-containing heterocycles due to its reactive nitrile and nitro functional groups.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Material Science: Investigated for the synthesis of specialized organic ligands and functional materials.

Basic Information

Product Name	3-Quinolinecarbonitrile, 1,4-Dihydro-7-Nitro-4-Oxo-
CAS No.	364794-10-5
Molecular Formula	C₁₀H₅N₃O₃
Molecular Weight	215.17 g/mol
Synonyms	7-Nitro-1,4-dihydro-4-oxoquinoline-3-carbonitrile; 7-Nitro-4-oxo-1,4-dihydroquinoline-3-carbonitrile; 1,4-Dihydro-7-nitro-4-oxo-3-quinolinecarbonitrile; 3-Cyano-7-nitro-4-hydroxyquinoline; 7-Nitro-4-hydroxyquinoline-3-carbonitrile; 4-Hydroxy-7-nitroquinoline-3-carbonitrile; AQX 0165
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarbonitrile, 1,4-Dihydro-7-Nitro-4-Oxo- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to minimize contact with moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.