Description

(3E)-3-(4-tert-Butoxy-Phenyl)Acrylic Acid CAS NO 364778-12-1 is a high-purity, functionalized cinnamic acid derivative characterized by its tert-butoxy phenyl substituent. This compound serves as a versatile and valuable pharmaceutical intermediate and organic building block for advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting inflammation, metabolic disorders, and central nervous system (CNS) diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators, leveraging its aromatic and acrylic acid functionalities.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor or core structure for electron-transport materials and emissive layer components in display and lighting technologies.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with specific optical or mechanical properties.
• Liquid Crystal & Dye Industries: Utilized as a synthetic intermediate for producing advanced dyes, pigments, and liquid crystal compounds.
• Academic & Industrial R&D: A crucial reagent in medicinal chemistry and material science research for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Product Name	(3E)-3-(4-tert-Butoxy-Phenyl)Acrylic Acid
CAS No.	364778-12-1
Molecular Formula	C13H16O3
Molecular Weight	220.26 g/mol
Synonyms	(E)-3-(4-(tert-Butoxy)phenyl)acrylic acid; 3-(4-tert-Butoxyphenyl)-2-propenoic acid; 4-tert-Butoxycinnamic acid; (E)-4-(tert-Butoxy)cinnamic acid; trans-3-(4-tert-Butoxyphenyl)acrylic acid; p-tert-Butoxycinnamic acid; 364778-12-1; (3E)-3-[4-(1,1-Dimethylethoxy)phenyl]-2-propenoic acid
EINECS	Contact for details

Quality Control

Our (3E)-3-(4-tert-Butoxy-Phenyl)Acrylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.