Description

6-Bromo-2-(4-Iodo-Phenyl)-Quinoline-4-Carboxylic Acid is a high-purity, multi-halogenated quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the development of novel compounds with specific electronic and steric properties. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, catalyst development, and the creation of functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Research: Used in the design and synthesis of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or a functional unit in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the presence of both bromo and iodo substituents, enabling sequential functionalization.
• Ligand Synthesis: Utilized for creating complex chelating ligands in coordination chemistry and catalysis.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	6-Bromo-2-(4-Iodo-Phenyl)-Quinoline-4-Carboxylic Acid
CAS No.	364383-14-2
Molecular Formula	C₁₆H₉BrINO₂
Molecular Weight	453.06 g/mol
Synonyms	6-Bromo-2-(4-iodophenyl)quinoline-4-carboxylic acid; 2-(4-Iodophenyl)-6-bromoquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-bromo-2-(4-iodophenyl)-; 364383-14-2; 6-Bromo-2-(p-iodophenyl)quinoline-4-carboxylic acid; 6-Br-2-(4-I-Ph)-Q-4-COOH
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-2-(4-Iodo-Phenyl)-Quinoline-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider using a desiccant and storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.