Description

2-Amino-7-(3,4,5-Trimethoxyphenyl)-7,8-Dihydroquinazolin-5(6H)-One is a sophisticated dihydroquinazolinone derivative, a key structural motif in medicinal chemistry. This compound matters as a high-value pharmaceutical intermediate and research chemical for developing novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery programs targeting various disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzymatic pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new chemical entities.
• Biochemical Probe Development: Employed in the design and creation of chemical probes for investigating biological mechanisms and target validation in cellular assays.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for constructing complex, nitrogen-containing heterocycles with specific substitution patterns.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) engaged in cutting-edge chemical biology and drug discovery projects.

Basic Information

Product Name	2-Amino-7-(3,4,5-Trimethoxyphenyl)-7,8-Dihydroquinazolin-5(6H)-One
CAS No.	364380-99-4
Molecular Formula	C17H19N3O4
Molecular Weight	329.35 g/mol
Synonyms	2-Amino-7-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydroquinazolin-5-one; 7-(3,4,5-Trimethoxyphenyl)-2-amino-7,8-dihydro-5(6H)-quinazolinone; 364380-99-4; 2-Amino-7-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydroquinazolin-5-one; 5(6H)-Quinazolinone, 2-amino-7,8-dihydro-7-(3,4,5-trimethoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 2-Amino-7-(3,4,5-Trimethoxyphenyl)-7,8-Dihydroquinazolin-5(6H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.