Description

tert-Butyl {5-Bromo-2-[4-(Methylthio)Phenoxy]Benzyl}Methylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its complex molecular structure featuring bromo, methylthio, and phenoxy functional groups. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with specific biological activities. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the discovery and production of new therapeutic agents, particularly within medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Active Pharmaceutical Ingredient (API) Synthesis: A crucial building block in the construction of the final molecular framework of target APIs.
• Chemical Biology Probes: Can be utilized to create specialized probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	tert-Butyl {5-Bromo-2-[4-(Methylthio)Phenoxy]Benzyl}Methylcarbamate
CAS No.	364324-01-6
Molecular Formula	C20H24BrNO3S
Molecular Weight	438.38 g/mol
Synonyms	tert-Butyl N-[(5-bromo-2-{[4-(methylsulfanyl)phenyl]oxy}phenyl)methyl]-N-methylcarbamate; Carbamic acid, N-[(5-bromo-2-[[4-(methylthio)phenoxy]phenyl)methyl]-N-methyl-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl N-[(5-bromo-2-{[4-(methylsulfanyl)phenyl]oxy}phenyl)methyl]-N-methylcarbamate; tert-Butyl (5-bromo-2-(4-(methylthio)phenoxy)benzyl)(methyl)carbamate; BOC-Protected Amine Intermediate 364324-01-6
EINECS	Contact for details

Quality Control

Our tert-Butyl {5-Bromo-2-[4-(Methylthio)Phenoxy]Benzyl}Methylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.