Description

Oxiranepropanol, 3-Ethynyl-, (2R,3S)- (9Ci) is a high-purity, chiral epoxide building block featuring both an oxirane ring and an ethynyl group, making it a versatile intermediate for advanced organic synthesis. Its defined stereochemistry at the 2R,3S configuration is critical for producing enantiomerically pure compounds with specific biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in developing targeted therapies and enzyme inhibitors.
• Agrochemical Research: Used in creating advanced, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Monomer: Employed in the development of specialized polymers and resins, where the epoxide and alkyne functionalities allow for cross-linking and post-polymerization modifications.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions via click chemistry reactions facilitated by the ethynyl group.
• Fine Chemical Synthesis: Acts as a versatile building block for the multi-step synthesis of complex natural products and other high-value specialty chemicals.

Basic Information

Item	Details
Product Name	Oxiranepropanol, 3-Ethynyl-, (2R,3S)- (9Ci)
CAS No.	362675-45-4
Molecular Formula	C7H8O2
Molecular Weight	124.14 g/mol
Synonyms	(2R,3S)-3-Ethynyloxiranemethanol; (2R,3S)-3-Ethynyl-2-oxiranemethanol; 3-Ethynyloxiran-2-ylmethanol, (2R,3S)-; (2R,3S)-Glycidylacetylene; (2R,3S)-3-Ethynylglycidol; 2-Oxiranemethanol, 3-ethynyl-, (2R,3S)-; Chiral Ethynyl Glycidol
EINECS	Contact for details

Quality Control

Every batch of Oxiranepropanol, 3-Ethynyl-, (2R,3S)- (9Ci) is manufactured and tested under strict quality management systems. We ensure compliance with relevant industry standards for chiral intermediates. Comprehensive analytical testing, including chiral HPLC, NMR, and GC, is performed to verify identity, purity, and enantiomeric excess. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original sealed packaging to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.