Description

1,6-Naphthyridine-8-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its rigid, fused bicyclic structure and bifunctional nature, making it a critical precursor for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in metal-organic frameworks (MOFs) and homogeneous catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and other functional organic materials.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological processes and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library production.

Basic Information

Product Name	1,6-Naphthyridine-8-Carboxylic Acid
CAS No.	362606-19-7
Molecular Formula	C9H6N2O2
Molecular Weight	174.16 g/mol
Synonyms	8-Carboxy-1,6-naphthyridine; 1,6-Naphthyridine-8-carboxylic acid; 8-Quinolinecarboxylic acid, 1,6-naphthyridine analog; 1,6-Diazanaphthalene-8-carboxylic acid; 1,6-Naphthyridin-8-ylcarboxylic acid; 8-(Carboxy)-1,6-naphthyridine; 1,6-Naphthyridine-8-ylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 1,6-Naphthyridine-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from moisture absorption and light exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.