Description

(2-(Trifluoromethyl)Quinolin-4-Yl)Methanol is a high-value, multifunctional quinoline derivative characterized by a trifluoromethyl group and a hydroxymethyl substituent. This compound is a crucial pharmaceutical intermediate and organic building block prized for its ability to impart unique physicochemical properties to target molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a core structure for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Ligand & Catalyst Development: Used in organometallic chemistry to create novel ligands for catalysis, leveraging the quinoline nitrogen and functional groups for metal coordination.
• Material Science: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport materials, due to its rigid, conjugated structure.
• Fluorine Chemistry Building Block: The trifluoromethyl group makes it a valuable precursor for introducing fluorine atoms into complex molecules to modulate lipophilicity, metabolic stability, and bioavailability.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent probes or molecular tags for biological imaging and diagnostic applications.

Basic Information

Product Name	(2-(Trifluoromethyl)Quinolin-4-Yl)Methanol
CAS No.	362469-45-2
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	4-(Hydroxymethyl)-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-quinolinemethanol; (2-Trifluoromethyl-4-quinolyl)methanol; Quinoline, 4-(hydroxymethyl)-2-(trifluoromethyl)-; 4-Quinolinemethanol, 2-(trifluoromethyl)-; 362469-45-2; 2-Trifluoromethylquinoline-4-methanol
EINECS	Contact for details

Quality Control

Our (2-(Trifluoromethyl)Quinolin-4-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.