Description

(+/-)-Methamphetamine-D14 CAS NO 362044-12-0 is a deuterium-labeled isotopologue of methamphetamine, where fourteen hydrogen atoms are replaced with the stable isotope deuterium. This compound is of critical importance as a certified reference material and an internal standard for precise quantitative analysis in forensic, clinical, and research laboratories. It is primarily needed by analytical chemists and researchers in toxicology, pharmaceutical development, and forensic science for applications requiring high specificity and accuracy, such as mass spectrometry and drug metabolism studies.

Application

• Internal Standard for Mass Spectrometry (GC-MS, LC-MS/MS): Essential for the accurate quantification of methamphetamine and its metabolites in complex biological matrices like urine, blood, and hair.
• Forensic Analysis and Toxicology: Used as a certified reference standard to confirm the identity and concentration of illicit methamphetamine in casework and regulatory compliance testing.
• Pharmacokinetic and Metabolism Studies: Enables the detailed tracking of drug absorption, distribution, metabolism, and excretion (ADME) in research settings.
• Method Development and Validation: Serves as a critical component in developing, calibrating, and validating new analytical methods to ensure reliability and reproducibility.
• Quality Control in Pharmaceutical Research: Provides a benchmark for purity and identity in the synthesis and analysis of novel pharmaceutical compounds.
• Stable Isotope Labeling Studies: Utilized in mechanistic studies to elucidate metabolic pathways and degradation products.

Basic Information

Product Name	(+/-)-Methamphetamine-D14
CAS No.	362044-12-0
Molecular Formula	C10H1D14N•HCl or C10D14H1N•HCl
Molecular Weight	~169.3 (Free base), ~205.8 (Hydrochloride salt) *
Synonyms	Methamphetamine-d14; N-Methyl-1-phenyl-2-aminopropane-d14; d14-Methamphetamine; (±)-Methamphetamine-d14; Dextro/Levo-Methamphetamine-d14; Amphetamine, N,α-dimethyl-, (αR)-, hydrochloride (1:1), d14-; N-Methylamphetamine-d14; DL-Methamphetamine-d14
EINECS	Contact for details

* Molecular weight is approximate and depends on the exact deuteration level and salt form. Contact us for precise specifications.

Quality Control

Our (+/-)-Methamphetamine-D14 is manufactured and handled under strict quality protocols to ensure the highest isotopic purity and chemical integrity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (Atom % D), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant standards for reference materials to guarantee reliable and reproducible performance in your critical assays.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at controlled room temperature (15-25°C) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98% (Chemical Purity)
Isotopic Purity (Atom % D)	≥98% (by MS)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.