Description

4-Fluoro-3-(3-Trifluoromethyl-Phenylsulfamoyl)-Benzoic Acid is a high-value, multi-functional benzoic acid derivative featuring both fluorine and sulfonamide pharmacophores. This compound is a critical advanced pharmaceutical intermediate (API) for the synthesis of novel active ingredients, offering unique reactivity and properties for modern drug discovery. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, leveraging its fluorinated aromatic structure.
• Material Science Precursor: Serves as a monomer or functionalizing agent for specialty polymers with enhanced chemical resistance.
• Ligand Synthesis: Employed in creating complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Utilized in the design of molecular probes for studying enzyme inhibition and biological pathways.

Basic Information

Product Name	4-Fluoro-3-(3-Trifluoromethyl-Phenylsulfamoyl)-Benzoic Acid
CAS No.	361157-20-2
Molecular Formula	C14H9F4NO4S
Molecular Weight	363.29 g/mol
Synonyms	4-Fluoro-3-[[[3-(trifluoromethyl)phenyl]amino]sulfonyl]benzoic acid; 3-[(3-Trifluoromethylphenyl)sulfamoyl]-4-fluorobenzoic acid; Benzoic acid, 4-fluoro-3-[[[3-(trifluoromethyl)phenyl]amino]sulfonyl]-; 4-Fluoro-3-(3-trifluoromethylphenylsulfamoyl)benzoic acid; 361157-20-2
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-3-(3-Trifluoromethyl-Phenylsulfamoyl)-Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and should be kept separate from incompatible materials. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.