Description

6-Methoxy-7-Nitro-3,4-Dihydroquinolin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its specific quinolinone core structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly as a key building block in kinase inhibitor synthesis. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Serves as a specialized starting material for constructing more complex heterocyclic compounds in academic and industrial research.
• Biochemical Tool Compound: Potential use in the development of biochemical probes for studying enzyme function and cellular signaling pathways.
• Fine Chemical Production: Employed in the custom synthesis of high-value, low-volume specialty chemicals for advanced applications.

Basic Information

Product Name	6-Methoxy-7-Nitro-3,4-Dihydroquinolin-2(1H)-One
CAS No.	359864-61-2
Molecular Formula	C₁₀H₁₀N₂O₄
Molecular Weight	222.20 g/mol
Synonyms	6-Methoxy-7-nitro-1,2,3,4-tetrahydroquinolin-2-one; 7-Nitro-6-methoxy-3,4-dihydro-2(1H)-quinolinone; 2(1H)-Quinolinone, 3,4-dihydro-6-methoxy-7-nitro-; 359864-61-2; 6-Methoxy-7-nitro-1,2,3,4-tetrahydroquinolin-2-one; 1,2,3,4-Tetrahydro-6-methoxy-7-nitro-2-quinolinone
EINECS	Contact for details

Quality Control

Our 6-Methoxy-7-Nitro-3,4-Dihydroquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.