Description

(1S,2S)-(-)-2-Amino-1-Cyclopentanecarboxylic Acid Hydrochloride is a high-purity, stereochemically defined amino acid derivative, essential for advanced pharmaceutical synthesis and research. Its core value lies in its role as a critical chiral building block for the development of novel therapeutics, particularly peptidomimetics and enzyme inhibitors. This product is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, including protease inhibitors and other biologically active molecules.
• Peptidomimetic Research: Used to construct constrained peptide analogs to enhance metabolic stability and receptor selectivity in drug discovery.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands and organocatalysts.
• Biochemical Research: Employed in studies of enzyme mechanisms and as a substrate analog in biochemical assays.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(1S,2S)-(-)-2-Amino-1-Cyclopentanecarboxylic Acid Hydrochloride
CAS No.	359849-58-4
Molecular Formula	C6H12ClNO2
Molecular Weight	165.62 g/mol
Synonyms	(1S,2S)-2-Aminocyclopentanecarboxylic acid hydrochloride; (1S,2S)-2-Amino-1-cyclopentanecarboxylic acid HCl; (1S,2S)-ACPC HCl; cis-2-Aminocyclopentanecarboxylic acid hydrochloride (1S,2S)-; (-)-cis-2-Aminocyclopentanecarboxylic acid hydrochloride; L-cis-ACPC hydrochloride; (1S,2S)-2-Amino-cyclopentanecarboxylic acid monohydrochloride
EINECS	Contact for details

Quality Control

Our (1S,2S)-(-)-2-Amino-1-Cyclopentanecarboxylic Acid Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to meet the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.